Whole eye transplantation (WET) remains experimental. Long presumed impossible, recent scientific advances regarding WET suggest that it may become a clinical reality. However, the ethical implications of WET as an experimental therapeutic strategy remain largely unexplored. This article evaluates the ethical considerations surrounding WET as an emerging experimental treatment for vision loss. A thorough review of published literature pertaining to WET was performed; ethical issues were identified during review of the articles.

Medical and public health research includes surveys, interviews, and biospecimens — techniques that do not present substantial risks to subjects. Consequently, this research is exempt from regulation under the Federal Common Rule. Nevertheless, at many institutions, exempt research is frequently subject to the same regulatory process that is required for non-exempt research, requiring the consumption of time and resources for review by Institutional Review Board members or staff. The federal government has indicated an intention to reform and centralize this system, (...) but has not yet specified the form that it will use instead. By examining the policies of the top 50 research institutions, this article assesses institutional practices surrounding exempt research, quantifies the extent of exempt-research review requirements, documents a problem of “over-compliance,” and makes recommendations for reform. (shrink)

This article summarizes the multitude of empirical studies that test ethical decision making in business and suggests additional research necessary to further theory in this area. The studies are categorized and related to current theoretical ethical decision making models. The studies are related to awareness, individual and organizational factors, intent, and the role of moral intensity in ethical decision making. Summary tables provide a quick reference for the sample, findings, and publication outlet. This review provides insights for understanding organizational ethical (...) decision constructs, where ethical decision making theory currently stands, and provides insights for future empirical work on organizational ethical decision making. (shrink)

Over the past three or four decades, the concept of medical ethics has changed from a limited set of standards to a broad field of debate and research. We define medical ethics as an arena of moral issues in medicine, rather than a specific discipline. This paper examines how the disciplines of health care ethics and health care law have developed and operated within this arena. Our framework highlights the aspects of jurisdiction and the assignment of responsibilities . This theoretical (...) framework prompted us to study definitions and changing responsibilities in order to describe the development and interaction of health care ethics and health law. We have opted for the context of the Dutch debate about end-of-life decisions as a relevant case study. We argue that the specific Dutch definition of euthanasia as ‘intentionally taking the life of another person by a physician, upon that person’s request’ can be seen as the result of the complex jurisdictional process. This illustrates the more general conclusion that the Dutch debate on end-of-life decisions and the development of the two disciplines must be understood in terms of mutual interaction. (shrink)

Over the past three or four decades, the concept of medical ethics has changed from a limited set of standards to a broad field of debate and research. We define medical ethics as an arena of moral issues in medicine, rather than a specific discipline. This paper examines how the disciplines of health care ethics and health care law have developed and operated within this arena. Our framework highlights the aspects of jurisdiction and the assignment of responsibilities. This theoretical framework (...) prompted us to study definitions and changing responsibilities in order to describe the development and interaction of health care ethics and health law. We have opted for the context of the Dutch debate about end-of-life decisions as a relevant case study. We argue that the specific Dutch definition of euthanasia as ‘intentionally taking the life of another person by a physician, upon that person’s request’ can be seen as the result of the complex jurisdictional process. This illustrates the more general conclusion that the Dutch debate on end-of-life decisions and the development of the two disciplines must be understood in terms of mutual interaction. (shrink)

Aan de orde komen opvattingen over (de rol van) vrouwen in het werk van westerse filosofen, te weten Plato, Aristoteles, St. Thomas Aquinas, Christine de Pisan, Bacon, Descartes, Rousseau, Kant, Wollstonecraft, Schopenhauer, Nietzsche, Irigaray.

This essay traces the history of premenstrual syndrome in French, British, and American medical literature from 1950 to 2004. Aetiological theories, treatments and diagnostic criteria have varied over time and place, reflecting local conditions and changing notions of objectivity and evidence. During the 1970s researchers in each nation utilised different research strategies to overcome variation and contradictory results characteristic of PMS research. Since the 1980s, attempts have been made to standardise research internationally through prospective daily rating questionnaires that diagnose and (...) measure PMS. Amidst controversy, a psychiatric reformulation of the syndrome was included in the Diagnostic and Statistical Manual of Mental Disorders . While the diagnostic criteria for this psychiatric category, now called premenstrual dysphoric disorder , are widely accepted for research purposes, efforts to transfer them to medical practice have been less successful. PMDD remains a contested disease construct. (shrink)

The nature of mental representations of linguistic expressions in relation to the time course from intention to articulation is a major issue. We discuss Branigan & Pickering's proposal to use structural priming to tap into this process. We show that their interpretation of their findings cannot be maintained. We reinterpret these results and suggest a revision of their conclusions.

Joan Mellen In the Realm of the Senses London: British Film Institute ISBN: 1 8445 7034 7.

This article is a case study of a woman-owned and-operated sexual products business, conceived in the midst of a fragmenting women's movement in 1977. The article tracks the evolution of pro-sex feminist ideology within this business during the past 22 years. Whereas most feminist organizations research focuses on nonprofit organizations and their relationship to the state, this study focuses on a political organization that depends on profits for survival. The voices in this study reveal the complexities of running an “alternative” (...) business during the 1980s and 1990s and of balancing political ideals with profit needs. Ironically, as Toy Box and its consumer base grow, more and more men and women are exposed to pro-sex feminism and buying into its philosophy. This contradiction is fundamental to the story of Toy Box's history and evolution. (shrink)

We study a generalization of the standard syntax and game-theoretic semantics of logic, which is based on a duality between two players, to a multiplayer setting. We define propositional and modal languages of multiplayer formulas, and provide them with a semantics involving a multiplayer game. Our focus is on the notion of equivalence between two formulas, which is defined by saying that two formulas are equivalent if under each valuation, the set of players with a winning strategy is the same (...) in the two respective associated games. We provide a derivation system which enumerates the pairs of equivalent formulas, both in the propositional case and in the modal case. Our approach is algebraic: We introduce multiplayer algebras as the analogue of Boolean algebras, and show, as the corresponding analog to Stone’s theorem, that these abstract multiplayer algebras can be represented as concrete ones which capture the game-theoretic semantics. For the modal case we prove a similar result. We also address the computational complexity of the problem whether two given multiplayer formulas are equivalent. In the propositional case, we show that this problem is co-NP-complete, whereas in the modal case, it is PSPACE-hard. (shrink)

Lindroos constructs an alternative interpretation on history, time, politics and art, approached through the moment of the Now (Jetztzeit). In the first section, she elaborates the critique of chronologic-linear way of understanding history. Through a close reading of Benjamin's "Work of Art" essay, the second section examines the problems of origins, authenticity and traditions of art through the ideas of artistic avant-garde and politicization of aesthetics. The end of the book discusses the concept of image and the new images as (...) an Image-Space (Bildraum) of action. (shrink)

In discussing the cultural history of the 19th century, Walter Benjamin diagnosed the emergence of the modern novel and its form of narration as the sign of a fracturing experience. The split in experience is related to the scattering of a homogeneous idea of space and time, constituted especially during the Enlightenment and in the German historicism. Benjamin's claim reflected the fracturing temporality of modern communities as well as the transformations in the understanding of the meaning of tradition. Here, I (...) begin by discussing Benjamin's conceptions of experience and memory in detail. Secondly, I consider his ideas on history in the framework of challenging the new forms of narration. In the end, I consider the loss of a unified community, especially by indicating ways in which the after-modern community reflects the relationship between aesthetics and politics in Jean-François Lyotard's thought. Key Words: Benjamin • community • experience • history • Lyotard • memory • narrative • remembrance • time. (shrink)

We present nine facets for the analysis of the past and future evolution of AI. Each facet has also a set of edges that can summarise different trends and contours in AI. With them, we first conduct a quantitative analysis using the information from two decades of AAAI/IJCAI conferences and around 50 years of documents from AI topics, an official database from the AAAI, illustrated by several plots. We then perform a qualitative analysis using the facets and edges, locating AI (...) systems in the intelligence landscape and the discipline as a whole. This analytical framework provides a more structured and systematic way of looking at the shape and boundaries of AI. (shrink)

This article provides a brief overview of several formal frameworks concerning the relation between knowledge on the one hand, and obligation on the other. We discuss the paradox of the knower, knowledge based obligation, knowingly doing, deontic dynamic epistemology, descriptive obligations, and responsibilities as dynamic epistemology.